Seven Seas Grandeur under way on calm blue water in June 2024

Seven Seas Grandeur / Regent Seven Seas Cruises

14-Night Panama Canal from Miami on Seven Seas Grandeur

Nights: 14
Ports of call: 9 to 10
Departures: 2
From: $9,849

Seven Seas Grandeur sails this route from PortMiami twice in the window we track. Each one runs 14 nights. It finishes in Panama City (Panama) rather than back in Miami, so check flights home before you book.

Every sailing calls at Harvest Caye (Belize), Roatan (Honduras), Georgetown (Grand Cayman, Cayman Islands), Puerto Limon (Costa Rica), and Colon (Panama). The other ports change with the date: there are 2 port combinations, each listed below with its own departure dates. We record which ports a sailing visits, not the order it visits them in.

Departures run from Tue, Feb 23, 2027 to Wed, Dec 22, 2027. The cheapest recorded starting fare is $9,849 per person, which works out at $704 a night.

Schedule last updated 2026-11-14 · 2 departures listed · Dates can change. Verify with the cruise line before booking.

Which ports, on which dates?

Via Costa Maya

Calls at Costa Maya (Mexico) · Harvest Caye (Belize) · Roatan (Honduras) · Georgetown (Grand Cayman, Cayman Islands) · Ocho Rios (Jamaica) · Puerto Limon (Costa Rica) · Cartagena (Spain) · Colon (Panama) · Panama Canal Transit

1 departure, from $11,299 per person

Tue, Feb 23, 2027

Via Key West

Calls at Key West (Florida) · Cozumel (Mexico) · Santo Tomas de Castilla (Guatemala) · Harvest Caye (Belize) · Roatan (Honduras) · Puerto Limon (Costa Rica) · Panama Canal (gatun Yacht Club) · Colon (Panama) · Falmouth (Jamaica) · Georgetown (Grand Cayman, Cayman Islands)

1 departure, from $9,849 per person

Wed, Dec 22, 2027

Every departure on this route

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14-Night Panama Canal departures on Seven Seas Grandeur
Departs	Nights	Itinerary & ports	From
Tue, Feb 23, 2027 ends Tue, Mar 9, 2027	14	14-Night Panama Canal Calls at Costa Maya (Mexico) · Harvest Caye (Belize) · Roatan (Honduras) · Georgetown (Grand Cayman, Cayman Islands) · Ocho Rios (Jamaica) · Puerto Limon (Costa Rica) · Cartagena (Spain) · Colon (Panama) · Panama Canal Transit Ends in Panama City (Panama)	from $11,299 $807 a night · per person suite, as of 2026-11-14
Wed, Dec 22, 2027 back Wed, Jan 5, 2028	14	14-Night Panama Canal Calls at Key West (Florida) · Cozumel (Mexico) · Santo Tomas de Castilla (Guatemala) · Harvest Caye (Belize) · Roatan (Honduras) · Puerto Limon (Costa Rica) · Panama Canal (gatun Yacht Club) · Colon (Panama) · Falmouth (Jamaica) · Georgetown (Grand Cayman, Cayman Islands)	from $9,849 $704 a night · per person suite, as of 2026-11-14 Lowest fare shown

FEB
23
Tuesday · 14 nights
14-Night Panama Canal
Calls at Costa Maya (Mexico) · Harvest Caye (Belize) · Roatan (Honduras) · Georgetown (Grand Cayman, Cayman Islands) · Ocho Rios (Jamaica) · Puerto Limon (Costa Rica) · Cartagena (Spain) · Colon (Panama) · Panama Canal Transit
Ends in Panama City (Panama)
Ends Tue, Mar 9, 2027 in Panama City
from $11,299 $807 a night · per person
suite, as of 2026-11-14
DEC
22
Wednesday · 14 nights
14-Night Panama Canal
Calls at Key West (Florida) · Cozumel (Mexico) · Santo Tomas de Castilla (Guatemala) · Harvest Caye (Belize) · Roatan (Honduras) · Puerto Limon (Costa Rica) · Panama Canal (gatun Yacht Club) · Colon (Panama) · Falmouth (Jamaica) · Georgetown (Grand Cayman, Cayman Islands)
Returns Wed, Jan 5, 2028
Lowest fare shown
from $9,849 $704 a night · per person
suite, as of 2026-11-14

Months this route sails

February 2027 1 December 2027 1

Other routes Seven Seas Grandeur runs

Full ship schedule

10-Night Eastern Caribbean Tortola (British Virgin Islands) · St. Thomas (U.S. Virgin Islands) · Roseau (Dominica) · Philipsburg (St. Maarten) · Gustavia (St. Barts) · St. John's (Antigua) · Basseterre (St. Kitts) · Puerto Plata (Dominican Republic) · San Juan (Puerto Rico) · Pointe-a-Pitre (Guadeloupe) · Fort-de-France (Martinique) · Castries (St. Lucia) 3 departures, 3 port combinations from $5,400 10-Night Western Caribbean Harvest Caye (Belize) · Roatan (Honduras) · Georgetown (Grand Cayman, Cayman Islands) · Costa Maya (Mexico) · Belize City (Belize) · Montego Bay (Jamaica) · Great Stirrup Cay (Bahamas) · Falmouth (Jamaica) · Progresso (Mexico) · Ocho Rios (Jamaica) 3 departures, 3 port combinations from $5,599 7-Night Western Caribbean Cozumel (Mexico) · Roatan (Honduras) · Costa Maya (Mexico) · Harvest Caye (Belize) · Belize City (Belize) 2 departures, 2 port combinations from $6,549

Starting fares per person, for the cheapest cabin listed, with taxes and port fees included, last updated 2026-11-14. Fares change often, so check the current price before you book.

Same region, different ship

All Transatlantic sailings

12-Night Transatlantic Queen Elizabeth 16-Night Transatlantic Oceania Marina 23-Night Transatlantic Oceania Marina 16-Night Transatlantic Explora I

Seven Seas Grandeur's 14-Night Panama Canal cruise: questions

When does Seven Seas Grandeur's 14-Night Panama Canal cruise leave Miami?

Seven Seas Grandeur's 14-Night Panama Canal cruise has 2 departures from Miami between February 2027 and December 2027. Most leave on a Tuesday, 1 of the 2.

Which ports does Seven Seas Grandeur's 14-Night Panama Canal cruise from Miami call at?

Every departure calls at Harvest Caye, Roatan, Georgetown, Puerto Limon, and Colon. The rest depends on the date: via Costa Maya on 1 departure and via Key West on 1 departure. The cards above list the dates for each.

How much does Seven Seas Grandeur's 14-Night Panama Canal cruise from Miami cost?

The lowest starting fare we recorded is $9,849 per person, for the cheapest cabin listed, with taxes and port fees included, on the 14-night sailing of Wed, Dec 22, 2027, about $704 a night. We checked it on November 14, 2026. Fares change daily, so check the current price before you book.