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Destination

Panama Canal cruises from Miami

Round trips of ten to twelve nights that sail into the canal from the Caribbean side, with Cartagena, Colón and Puerto Limón, and longer one-way voyages that go all the way through it and up the Pacific coast to Los Angeles, San Diego or Seattle.

There are 44 such sailings on the board, running 9 to 34 nights, operated by Norwegian Cruise Line, Holland America Line, Oceania Cruises, Virgin Voyages, MSC Cruises, Explora Journeys, Regent Seven Seas Cruises, Azamara, and Cunard aboard Norwegian Sun, Zuiderdam, Oceania Marina, Brilliant Lady, MSC Poesia, Explora III, Norwegian Joy, Oceania Vista, Norwegian Gem, Oceania Sonata, Norwegian Jewel, Seven Seas Grandeur, Azamara Quest, Queen Anne, and Norwegian Encore. The lowest recorded starting fare is $619 per person, on the Wed, Nov 18, 2026 departure.

Ports of call

Cartagena (Colombia)40 Panama Canal34 Colon (Panama)32 Puerto Limon (Costa Rica)27 Georgetown (Grand Cayman, Cayman Islands)19 Cozumel (Mexico)16 Falmouth (Jamaica)12 Harvest Caye (Belize)12 Great Stirrup Cay (Bahamas)11 Puerto Quetzal (Guatemala)11 Aruba10 Curaçao10 Cabo San Lucas (Mexico)10 Roatan (Honduras)8 Puntarenas (Costa Rica)7 Costa Maya (Mexico)5 Cabo Rojo (Dominican Republic)4 Santo Tomas de Castilla (Guatemala)4 Panama City (Panama)4 Ocho Rios (Jamaica)4 Belize City (Belize)4 Montego Bay (Jamaica)4 Manzanillo (Mexico)4 Huatulco (Mexico)3 Acapulco (Mexico)3 San Diego (California)3 Los Angeles (California)3 Puerto Caldera (Costa Rica)3 Puerto Vallarta (Mexico)3 Santa Marta (Colombia)2 Zihuatanejo (Mexico)2 Ensenada (Mexico)2 Seattle (Washington)1 Ketchikan (Alaska)1 Icy Strait (Alaska)1 Juneau Alaska1 Tracy Arm (Alaska)1 Victoria (British Columbia)1 Mazatlan (Mexico)1 Bonaire1 St. George's (Grenada)1 Bridgetown (Barbados)1 Castries (St. Lucia)1 Pointe-a-Pitre (Guadeloupe)1 Tortola (British Virgin Islands)1 Key West (Florida)1 Panama Canal (gatun Yacht Club)1 Bocas Del Toro (Panama)1 Kona (Hawaii)1 Honolulu (Oahu, Hawaii)1 Lautoka (Fiji)1 San Francisco (California)1
Schedule last updated · 44 departures listed · Dates can change. Verify with the cruise line before booking.

Your Panama Canal options

All routes

The 44 departures below run 24 different routes, cheapest per night first.

Distinct itineraries available, cheapest per night first
ItineraryNightsFrom
11-Night Panama Canal

Calls at Great Stirrup Cay (Bahamas) · Cartagena (Colombia) · Panama Canal · Colon (Panama) · Puerto Limon (Costa Rica) · Falmouth (Jamaica) · Georgetown (Grand Cayman, Cayman Islands)

Next on Wed, Nov 18, 2026

11$619$56 a night
18-Night Panama Canal

Calls at Cartagena (Colombia) · Colon (Panama) · Huatulco (Mexico) · Cabo San Lucas (Mexico) · San Diego (California) · Los Angeles (California)

Ends in Seattle (Washington)

Next on Thu, Apr 8, 2027

18$1,317$73 a night
29-Night Panama Canal

Calls at Ocho Rios (Jamaica) · Cartagena (Colombia) · Colon (Panama) · Puerto Limon (Costa Rica) · Roatan (Honduras) · Belize City (Belize)

Ends in Cartagena (Colombia)

Next on Sun, Mar 28, 2027

29$2,769$95 a night
15-Night Panama Canal

Calls at Cartagena (Colombia) · Panama Canal · Puerto Quetzal (Guatemala) · Manzanillo (Mexico)

Ends in Los Angeles (California)

Next on Sun, Jan 23, 2028

15$1,739$116 a night
12-Night Panama Canal

Calls at Great Stirrup Cay (Bahamas) · Cabo Rojo (Dominican Republic) · Aruba · Curaçao · Cartagena (Colombia) · Colon (Panama) · Panama Canal · Puerto Limon (Costa Rica)

Next on Mon, Dec 21, 2026

12$1,459$122 a night
16-Night Panama Canal: Miami To Los Angeles

Calls at Cartagena (Colombia) · Colon (Panama) · Puntarenas (Costa Rica) · Puerto Quetzal (Guatemala) · Cabo San Lucas (Mexico)

Ends in Los Angeles (California)

Next on Fri, Mar 26, 2027

16$2,064$129 a night
14-Night Panama Canal

Calls at Cartagena (Colombia) · Panama Canal · Puntarenas (Costa Rica) · Puerto Quetzal (Guatemala) · Huatulco (Mexico) · Acapulco (Mexico) · Cabo San Lucas (Mexico)

Ends in San Diego (California)

Next on Sat, Jan 2, 2027

14$1,899$136 a night
15-Night Repositioning

Calls at Cartagena (Colombia) · Colon (Panama) · Panama Canal · Puerto Caldera (Costa Rica) · Puerto Quetzal (Guatemala) · Puerto Vallarta (Mexico) · Cabo San Lucas (Mexico)

Ends in Los Angeles (California)

Next on Wed, Apr 21, 2027

15$2,099$140 a night

Starting fares per person, for the cheapest cabin listed, with taxes and port fees included, last updated . Fares change often, so check the current price before you book.

Every departure by date

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By month

Other destinations from Miami

Starting fares per person, for the cheapest cabin listed, with taxes and port fees included, last updated . Fares change often, so check the current price before you book.

Panama Canal from Miami: questions

How many Panama Canal cruises leave Miami?

44 Panama Canal cruises leave Miami, across 13 months, on 15 ships from Norwegian Cruise Line, Holland America Line, Oceania Cruises, Virgin Voyages, MSC Cruises, Explora Journeys, Regent Seven Seas Cruises, Azamara, and Cunard.

How long are Panama Canal cruises from Miami?

From 9 to 34 nights. The most common length is 11 nights, on 10 of the 44 sailings.

Which ports do Panama Canal cruises from Miami call at?

Most commonly Cartagena (40 sailings), Panama Canal (34 sailings), Colon (32 sailings), Puerto Limon (27 sailings), and Georgetown (19 sailings).